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[2] The human ALS-deficiency picture reinforces the same point from the opposite direction: profoundly reduced circulating IGF-1 is compatible with near-normal growth when local tissue IGF-1 is intact, underscoring that the circulating pool and the local pool are not simply interchangeable

Similar to the results of animal experiments, the high expression of IGF-1 in patients strongly associated with increased pain score

doi: 10.1515/REVEH-2022-0032 32

But this man was frightened and worried

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