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For the purpose of this study, 10 to 12 week old inbred male Lewis rats weighing approximately 300 grams each were used

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The ent -9-D 1t -PhytoP was prepared in 2009 by Durand and colleagues following a procedure developed for the synthesis of 15-D 2t -IsoP and 15- epi -15-E 2t -IsoP