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Context-dependent indicates heterogeneity across tissues, disease stages, or models

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SAFE-TBI Investigators

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Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS

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Combining erastin with vitamin C has been shown to increase intracellular ferrous iron levels via the AMPK/Nrf2/HMOX1 axis, resensitizing PDAC cells to ferroptosis and presenting a novel therapeutic approach [151]

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The production, concentration and purification protocols were improved [183]

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