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Elevated TMAO levels have been linked to a number of diseases, including cardiovascular and neurological disorders, renal disease, metabolic syndrome, obesity, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), cancer, and severe COVID-19

Dietary supplements do not replace a varied and balanced diet and a healthy lifestyle

Simcox J, Geoghegan G, Maschek JA, Bensard CL, Pasquali M, Miao R, et al

Although in cognitively healthy individuals differences in BBB uptake have been observed with APOE genotypes as early as in individuals in their 30s (Yassine et al., 2017) in mice older ages may be required for such disturbances to occur (Alata et al., 2015)

Inhibiting various mitochondrial enzymes, has shown that it can selectively kill neurons [78]