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Conversion of 5-OP to Glu by 5-Oxoprolinase The 5-OP that is the result of CHAC-catalyzed glutathione cleavage is converted to Glu by 5-oxoprolinase (OPLAH) in an ATP-dependent manner [122]

As a consequence, the increased expression of GST often translates to a poor prognosis in gliomas [109,110,111,112]

[DOI] [PubMed] [Google Scholar] 121.Nair N., Patrick H., Narula J

[DOI] [PubMed] [Google Scholar] Veiga-da-Cunha M., Tyteca D., Stroobant V., Courtoy P.J., Opperdoes F.R., Van Schaftingen E

Curcumin has been shown to reduce the activity of oncogenic lncRNAs including H19 and MALAT1, which stops tumor cells from growing and epithelial mesenchymal transition (EMT) in cancers like breast, liver, and colorectal cancer