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In preliminary experiments Emp1 was shown to be essential for viability and to influence ER glutathione levels, leading to a more oxidizing ER environment upon overexpression

Similarly, alcohol metabolism by CYP2E1 enzyme generates reactive oxygen species including hydrogen peroxide (H2O2), superoxide and hydroxyl radicals which have important roles in causing damage to DNA and in fatty acid oxidation

Increase of Catecholamines in Mouse Brain by Systemic Administration of -Glutamyl L-3,4-Dihydroxyphenylalanine