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Spine 26 , 15221527 (2001)

Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons

Scientific evidence suggests that oral and topical supplementation are the most reasonable and safe and are expected to cause mild side effects

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At 8-12 weeks is when the long-term cognitive and mood-stabilizing effects take hold, along with the less outwardly expressed benefits of the peptide (i.e., reduced inflammation, improved immune function, and neuroprotection)
