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Additionally, the results demonstrated that GSH (1 mM) rapidly degrades the disulfide bond in S-PTX (20 M), resulting in 52% of S-PTX (20 M) remaining after 10 min of reaction

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In addition to the enzymes related to lactate metabolism and Kla, the identification of an increasing number of Kla and their regulatory sites opens up new directions for tumor therapy

was further supported within the project EXC-2124/1-05.037_0 under Germanys Excellence StrategyEXC 2124 390838134 (Cluster of Excellence Controlling Microbes to Fight Infections) and by the German Center for Infection Research (DZIF) within the Deutsche Zentren der Gesundheitsforschung (funded by the German Ministry of Education and Research), grant no

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