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Description
A mutation in ubiquitin C-terminal hydrolase L1 (UCH-L1), which is associated with familial PD, was reported to inhibit CMA autophagy by interacting with the lysosomal receptor of CMA LAMP-2A [67]
Peripheral inflammatory cytokines can enter the CNS through the blood-brain barrier (BBB) or specific transporters [64]
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Fortunately, other foods are more amenable to treatment with gluten-degrading enzymes
