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One long-term trial found that taking 800mg daily for four years improved CRP levels and glucose control.36 1,2001,800mg/day Higher doses in this range have been explored in short-term studies, particularly for more advanced cases of neuropathy or obesity

Eosinophil-derived MMP-9 is found in basal cell and squamous cell carcinomas95,96 and in bullous pemphigoid lesions.97 MMP-9 cleaves type XVII collagen (BP 180), a transmembrane molecule of the epidermal hemidesmosome, likely contributing to or causing basement membrane zone separation in bullous pemphigoid

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