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doi: 10.1523/JNEUROSCI.0823-20.2020 [DOI] [PMC free article] [PubMed] [Google Scholar] 13
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This patient's history of a childhood febrile heart condition and current presentation of severe heart failure make chronic rheumatic heart disease much more likely than MVP
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Oxidative stress activates the ASK1-JNK pathway, leading to JNK translocation to mitochondria, further exacerbating mitochondrial damage
