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*Correspondence: Ferdinando Franzoni, [email protected] These authors have contributed equally to this work This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The cells were then harvested and lysed with B-PER containing 5mM imidazole, 1X cOmplete, Mini, EDTA-free Protease Inhibitor Cocktail (Roche)

[1] In an average adult, only a small amount (approximately 10% of a therapeutic paracetamol dose) of NAPQI is produced, which is inactivated by conjugation with glutathione (GSH)