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In the brain, MAO-B converts it into a neurotoxin, MPP+, which can cause cell death in dopamine-producing neurons in the substantia nigra

Dietary carnitine is taken up from the intestinal lumen into the enterocyte by an active transport mechanism, but it passes across the serosal membrane into the circulation by simple diffusion

Multicenter clinical placebo-controlled study with acetyl-L-carnitine in the treatment of mildly demented elderly patients

More research is necessary to confirm carnitine's potential for increasing TMAO levels and the various factors potentially involved like dose, form, treatment duration, and individual factors like diet and activity level of the person supplementing it

Effects of carnitine on thyroid hormone action