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J Biol Chem (2016) 291(29):1526781

doi: 10.1016/j.jep.2016.09.029 169

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All except one case were carriers of the same mutation, S467C.18 This is change of Serine to Cysteine at codon 467

247 Another meta-analysis of 20 randomized controlled trials in Alzheimer disease patients also noted likely benefits of huperzine A on cognitive function