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Description
The selectivity towards AChE over BuChE may help to alleviate undesirable side effects associated with inhibition of BuChE
As acetyl-CoA stores are depleted, the synthesis of NAGA an important cofactor of CPS I from acetyl-CoA and glutamate by NAGA synthetase is decreased
Sen A, De Castro I, Defranco DB, Deng FM, Melamed J, Kapur P, et al
10.1016/j.cell.2010.07.011 182 ZimmersT
Mol Neurobiol 57:30753088
