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patients in both arms received folic acid, vitamin B 12, and dexamethasone [see Dosage and Administration (2.4)]

[56] [57] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency, pregnancy, oral contraceptive use, haptocorrin deficiency, and myeloma

Pregnancy and breastfeeding: Avoid use without explicit clinician guidance due to limited safety data

Abstract Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes significant morbidity and mortality, and is becoming an increasingly common health problem because of the increasing longevity and prevalence of predisposing factors such as sedentary lifestyle, obesity and nutritional habits

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