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Researchers found that a protective enzyme called GPX4 which prevents a specific type of cell death called ferroptosis is significantly reduced in the granulosa cells of women with declining ovarian reserve

doi: 10.18632/aging.202827

Mice were initially group housed (three/cage) and allowed to acclimate to the colony environment maintained at a constant temperature (2123C) and humidity (4050%) on a 12-hour light-dark cycle (lights on 06001800 h)

Li et al, 2018a
