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The novel agent, -lipoic acid, can cause the development of insulin autoimmune syndrome

MTHFR polymorphisms, particularly C677T and A1298C, pose further challenges to folate metabolism, leading to the accumulation of unmetabolized folic acid (UMFA), which is associated with increased oxidative stress
Farhang says
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Wang Y, Sun J, Zhu K, Wang D, Zhao X, Zhang H, et al