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A study conducted by the Panel on Dietetic Products for the European Food Safety Authority in 2017 concluded that ergothioneine is safe for children above 3 years of age and the general adult population, including pregnant and breastfeeding women

Qushi Huayu Decoction reduces liver injury in NASH by suppressing the MAPK pathway to protect the colonic tight junction and alters serum lipids by regulating the gut microbiota, including Bacteroides, Blautia, Lachnoclostridium and Turicibacter [157, 158]