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The direct comparison upon using the same concentration of ruthenium of the molecular agent Ru(II)-OH and NP4 showed a significantly higher tumor accumulation of the nanoparticle formulation NP4 (Supplementary Fig

doi: 10.3390/nu11092175 71

Hepatoma cell lines typically lack the CYP450 activity to generate the reactive metabolite of APAP observed in vivo, but are still subject to APAP cytotoxicity

Effects of polyphenols on oxidative stress-mediated injury in cardiomyocytes
Writing review & editing: Qianwen Zhang, Yuanrong Ju, Yan Ma, Tao Wang