lipid granules c elegans gut are sites of fat storage in embryos. Nile Red– (B) and Single-tissue proteomics in Caenorhabditis elegans

Biomed Chromatogr 33(7):e4533 Haycock PC et al (2016) Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

doi: 10.1371/journal.pone.0021347 103 KulkarniSSJoffraudMBoutantMRatajczakJGaoAWMaclachlanCet al

Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway

Plasma SPARC levels positively correlate with lumbar spine BMD, and 12 months of recombinant human parathyroid hormone (134) treatment in osteoporotic patients increases the circulating SPARC level, which is associated with changes in lumbar BMD at L2-L4 [24]

You might be wondering why is it so important to remove all of the excess fat