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Description
MDM2 mediates the ubiquitin-dependent degradation of SPY1, resulting in a downregulation of SPY1 expression, which in turn upregulates the expression of ALOX15 and growth differentiation factor 15 (GDF15), while decreasing the levels of GCH1, GPX4, and GSH
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Melanin, however, is the primary determinant of skin color [8,9,10]
It is no longer considered merely a neurohypophyseal hormone as its actions are considered to be far-reaching and include interaction with additional peptides
SA00013-2, Lot No
