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The reason for the age-dependent susceptibility to cuprizone is currently not clear

UV Exposure: What You Need to Know
Nat Rev Drug Discov 15 , 379380, (2016)

Pregnant Vitamin B12 is generally considered safe for use by pregnant women

Regarding IBD, 1 year after anti-TNF- discontinuation 42% of CD patients and 28% of UC patients experience a disease flare [155]
