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Description
With the development of nanotechnology, the biomaterials-based nanoagents may achieve passive (e.g., ELVIS and Bionic effect, pH, ROS and enzyme-dependent) or active (specific ligand or non-serum based biomarkers dependent) targeting and other functional effects (e.g., multi-enzyme activities, anti-inflammation and anti-oxidation effect) for AP treatment
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Basic Res Cardiol 103:444453

10.1074/jbc.M110.121327 J Biol Chem
Deficiencies in B12 or defects in methionine synthase will result in 5-methyl-THF trapping with the result being the development of megaloblastic anemia due to the block in nucleotide production and the inability of bone marrow erythroblasts to proceed through S-phase of the cell cycle
