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and preclinical studies in several disease indications as well as translational clinical trials

doi: 10.1016/S0015-0282(02)04237-1 62 Abd-ElmoatyMASalehRSharmaRAgarwalA

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We extended a pipeline used to analyse mtDNA variation in gnomAD 21 , now constructing self-reference sequences for each sample using homoplasmic and homozygous calls on the mtDNA and reference nucDNA regions of mtDNA origin (NUMTs

In addition, whether combination therapy might increase drug toxicity remains uncertain
